EuroPainClinicsStudy IX ( EPCS IX )

This prospective investigator-initiated study compares the clinical effectiveness and safety of epiduroscopic adhesiolysis in patients with failed back surgery syndrome (FBSS) and in patients with lumbar radicular pain without prior lumbar surgery. Epiduroscopy allows direct visualization of the epidural space with targeted mechanical adhesiolysis and optional epidural pharmacologic treatment. The primary objective is to evaluate pain relief and functional improvement following the procedure. Secondary outcomes include disability scores, quality of life, and procedure-related complications. The study aims to determine whether prior lumbar surgery influences clinical outcomes after epiduroscopic treatment.

NCT Number	NCT07411950
Lead Sponsor	EPC Education s.r.o. Collaborators: Slovak Academy of Sciences, East Slovak Institute for Cardiovascular Diseases
Conditions	Failed Back Surgery Syndrome, Lumbar Radiculopathy, Chronic Low Back Pain, Epidural Fibrosis
Enrollment	141 participants
Start Date	2021-01-01
Primary Completion	2025-05-31 (estimated)
Study Completion	2025-11-30 (estimated)
Updated on ClinicalTrials.gov	2026-02-17