Clinical Trial

Optimizing Operational Parameters for Diagnostic Vitrectomy

Study acronym: CELLVIT
Not Yet Recruiting
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Summary
Single-center ex-vivo study using blood samples from healthy donors processed through a 25-gauge vitrectomy system. The study compares four combinations of operational parameters (vacuum pressure and cut rate) to evaluate their impact on cellular recovery and morphological preservation. Pre- and post-procedure complete blood counts and cytology smears will be analyzed to identify the settings that minimize cell loss and mechanical damage, with the ultimate goal of optimizing diagnostic yield in vitreoretinal lymphoma (VRL) vitrectomy.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-02-05.
Trial Details
NCT Number NCT07408466
Lead Sponsor IRCCS San Raffaele
Conditions No Disease or Condition is Being Studied
Enrollment 100 participants
Start Date 2026-04
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-02-17