The Impact of Helicobacter Pylori Eradication on the Vaginal Microecology Change

This clinical controlled study enrolled 73 H. pylori（Helicobacter Pylori ）-infected female participants, stratified into reproductive-age and menopausal cohorts, alongside 10 non-infected controls. Through integrated analysis of routine vaginal discharge parameters and longitudinal amplicon sequencing data of vaginal discharge, investigators analyzed the impact of H. pylori eradication therapy on vaginal microecology.

NCT Number	NCT07408271
Lead Sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions	Helicobacter Pylori Infection, Helicobacter Pylori Eradication Antibiotic
Enrollment	83 participants
Start Date	2023-03-24
Primary Completion	2023-03-24 (estimated)
Study Completion	2024-03-24 (estimated)
Updated on ClinicalTrials.gov	2026-02-13