Quality of Life and Lymphedema After Surgical Treatment of Gynecological Malignancies

This prospective clinical study evaluates the accuracy of the currently used planning target volume (PTV) safety margin of 0.5 cm for stereotactic body radiotherapy (SBRT) of lung tumors at the Institute of Oncology Ljubljana. The study will assess setup errors and intrafractional motion using cone beam CT (CBCT) imaging in patients treated on three linear accelerators and with two different immobilization systems (vacuum cushion and long thermoplastic mask). Based on the collected data, the study aims to determine whether the current PTV margin is adequate and whether the SBRT setup protocol could be optimized.

NCT Number	NCT07407179
Lead Sponsor	Institute of Oncology Ljubljana
Conditions	Gynecologic Cancer
Enrollment	40 participants
Start Date	2022-06-01
Primary Completion	2022-12-31 (estimated)
Study Completion	2022-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-18