Clinical Trial

A Study to Evaluate Folate Receptor Alpha (FRα) Expression in Adult Participants With Ovarian, Fallopian Tube, and Primary Peritoneal Cancer in Italy

Study acronym: FORCE
Recruiting
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Summary
The purpose of this study is to evaluate the prevalence of folate receptor alpha (FRα)-positive status (≥75% viable tumor cells with moderate (2+) and/or strong (3+) membrane staining) in participants with high-grade serous ovarian, fallopian tube, and primary peritoneal cancer, stratified by time of sampling (initial diagnosis versus relapse), adhering to Ventana folate receptor alpha (FOLR1) RxDx (prescription diagnosis) assay Interpretation Guidance.
Protocol Amendment History 3 changes
critical Recruitment opened 2026-07-28
notable Primary completion pushed: 2026-07 -> 2026-11 2026-07-28
minor Completion pushed: 2026-07 -> 2026-11 2026-07-28
Trial Details
NCT Number NCT07407062
Lead Sponsor AbbVie
Conditions Cancer - Ovarian
Enrollment 200 participants
Start Date 2026-06-26
Primary Completion 2026-11 (estimated)
Study Completion 2026-11 (estimated)
Updated on ClinicalTrials.gov 2026-07-27