A Brief Video Intervention to Improve Patient Outcomes Following Radioiodine Treatment

This study will test the impact of a short video intervention for people who are receiving radioiodine treatment for thyroid conditions (such as hyperthyroidism or thyroid cancer). After their single-dose treatment, patients need to follow safety instructions to protect others and manage side effects during recovery. Some people find these instructions hard to remember, and side effects (or anticipation of side effects) can feel worrying or disruptive. The video aims to present the treatment information in a more accessible patient-friendly way, so that patients feel less distressed, find their side effects easier to cope with, and better engage with safety precautions. All patients will first have a pre-treatment consultation with their doctor and receive the standard treatment information currently provided. Before this consultation patients will be randomly assigned to view one of two videos. The control group will see a neutral video that details standard health information that is not specific to radioiodine, while the intervention group will see a video that explains side effects, safety requirements and recovery period in a more adaptive way. Comparing these two groups will allow us to assess whether this new approach improves coping, reduces distress, and enhances adherence to safety instructions in the post-dose recovery phase of radioiodine treatment.

NCT Number	NCT07405320
Lead Sponsor	University of Auckland, New Zealand
Conditions	Thyroid Cancer, Hyperthyroidism, Radioiodine Treatment
Enrollment	80 participants
Start Date	2026-01-12
Primary Completion	2026-07-06 (estimated)
Study Completion	2026-07-06 (estimated)
Updated on ClinicalTrials.gov	2026-02-12