Clinical Trial

Rivaroxaban in Idiopathic Membranous Nephropathy

Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
Through a prospective, single-center, randomized controlled trial, we aim to determine the thromboprophylactic efficacy of rivaroxaban in patients with idiopathic membranous nephropathy (IMN). IMN patients at high risk of thrombosis and low risk of bleeding will be enrolled and randomly assigned to a rivaroxaban group or a control group (receiving warfarin). Prophylactic anticoagulation will be administered with rivaroxaban or warfarin accordingly. Over the 6 months following initiation of prophylactic anticoagulation, the incidence of the primary efficacy endpoint (a composite of pulmonary embolism, deep vein thrombosis, and lower-extremity deep vein thrombosis) and the safety endpoint (bleeding events) will be compared between the two groups.
Trial Details
NCT Number NCT07404436
Lead Sponsor Beijing Friendship Hospital
Conditions Idiopathic Membranous Nephropathy
Enrollment 134 participants
Start Date 2024-01-05
Primary Completion 2026-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-11