Clinical Trial

M-TAPA vs ESPB for Postoperative Analgesia After Laparoscopic Cholecystectomy

Not Yet Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated February 13, 2026 (before its estimated July 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
Postoperative pain after laparoscopic cholecystectomy can negatively affect patient comfort, recovery, and opioid consumption. Regional abdominal wall blocks are commonly used as part of multimodal analgesia to improve postoperative pain control and reduce opioid-related side effects. The modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) and the erector spinae plane block (ESPB) are two ultrasound-guided regional anesthesia techniques that have been shown to provide effective postoperative analgesia in abdominal surgery. However, comparative clinical data between these two techniques in laparoscopic cholecystectomy are limited. This randomized, single-blind clinical trial aims to compare the postoperative analgesic effectiveness of M-TAPA and ESPB in adult patients undergoing elective laparoscopic cholecystectomy. Postoperative pain scores, opioid consumption, time to first analgesic requirement, and patient satisfaction will be evaluated.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-02-04.
Trial Details
NCT Number NCT07403682
Lead Sponsor Başakşehir Çam & Sakura City Hospital
Conditions Postoperative Pain, Cholecystectomy, Laparoscopic
Enrollment 124 participants
Start Date 2026-03-01
Primary Completion 2026-07-30 (estimated)
Study Completion 2026-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-13