Clinical Trial

HARMONY Trial : To Evaluate a Therapeutic and Monitoring Device(NOVAtria System) for Heart Failure Management

Recruiting
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Summary
The objective of the HARMONY trial is to evaluate the safety and efficacy of implantable left atrial pressure sensor and interatrial shunt system for the treatment of chronic heart failure with reduced left ventricular ejection fraction (HFrEF, EF ≤ 40%) and New York Heart Association(NYHA) functional Class II or Class III who at baseline are treated with guideline-directed drug and device therapies.
Protocol Amendment History 1 change
notable Trial sites expanded: 1 -> 15 locations 2026-05-09
Trial Details
NCT Number NCT07402239
Lead Sponsor United Innomed(Shanghai) Limited
Conditions Heart Failure
Enrollment 330 participants
Start Date 2026-03-16
Primary Completion 2028-06 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-05-08