Amputations in Childhood and Neuropathic Pain

This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood. The study focuses on two types of neuropathic pain: phantom limb pain and residual limb pain. It also evaluates quality of life and functional autonomy in this population and explores potential associations between neuropathic pain, autonomy, quality of life, and age at amputation. Using a mixed retrospective and prospective design, data are collected from medical records and standardized questionnaires administered during routine follow-up visits at a specialized pediatric limb anomaly center. The study seeks to improve understanding of neuropathic pain after pediatric amputation and its impact on daily functioning.

NCT Number	NCT07401966
Lead Sponsor	Hopitaux de Saint-Maurice
Conditions	Pediatric, Neuropathic Pain, Phantom Limb Pain, Amputation
Enrollment	50 participants
Start Date	2026-02-19
Primary Completion	2026-11-09 (estimated)
Study Completion	2027-02-02 (estimated)
Updated on ClinicalTrials.gov	2026-02-23