Fecal Microbiota Transplantation in an Expanded Ulcerative Colitis Population

This is a multi-centre, randomised controlled trial comparing fecal microbiota transplantation to placebo in an expanded ulcerative colitis population: a feasibility study (FRONTIER-UC) to determine whether a full-scale randomized controlled trial (RCT) to investigate fecal microbiota transplantation (FMT) in ulcerative colitis (UC) is feasible.

NCT Number	NCT07401680
Lead Sponsor	University of Alberta Collaborators: University of Calgary
Conditions	Ulcerative Colitis, Inflammatory Bowel Diseases, Clostridioides Difficile Infection
Enrollment	85 participants
Start Date	2026-03-01
Primary Completion	2028-03-01 (estimated)
Study Completion	2028-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-04