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Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy

StatusRecruiting
PhasePhase 4
Started2026-03-02
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 5 months later Jul 2026 → Jan 2027
See other at-risk trials from Cedars-Sinai Medical Center

Amendment history

2026-10-01
notable
Recruitment opened
Primary completion pushed: 2026-07 → 2027-01
Completion pushed: 2026-08 → 2027-01
Postoperative shoulder pain is often reported to be particularly bothersome after laparoscopy. The benefits of local anesthetic, such as bupivacaine, applied to subcutaneous tissue for general postoperative pain management after surgery is well established. However, there have been no studies on sprayed bupivacaine over the diaphragm to reduce shoulder pain in laparoscopic surgery. The purpose of the study is to evaluate if sprayed infra-diaphragmatic bupivacaine compared to placebo (saline) will improve postoperative shoulder pain in patients undergoing benign laparoscopic gynecologic surgery. The entire study will be conducted at Cedar Sinai Medical Center.
Trial Details
NCT Number NCT07400146
Lead Sponsor Cedars-Sinai Medical Center
Conditions Postoperative Pain, Shoulder Pain
Enrollment 100 participants
Start Date 2026-03-02
Primary Completion 2027-01 (estimated)
Study Completion 2027-01 (estimated)
Updated on ClinicalTrials.gov 2026-09-30