Clinical Trial

Discontinuation of Antiplatelet Therapy After Drug-Coated Balloon Treatment

Not Yet Recruiting
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Summary
The goal of this clinical trial is to evaluate the benefits and risks of discontinuing antiplatelet therapy on clinical outcomes in patients who previously underwent coronary intervention using a drug-coated balloon. The main questions it aims to answer are: Does stopping antiplatelet therapy after 12 months affect the risk of net adverse clinical events? Does stopping antiplatelet therapy reduce the risk of bleeding compared with continuing treatment? Researchers will compare patients who discontinue antiplatelet therapy with patients who continue antiplatelet therapy to determine the impact on clinical outcomes during follow-up. Participants will: Be randomly assigned to either discontinue or continue antiplatelet therapy Receive routine clinical follow-up through clinic visits or telephone contacts Be monitored for cardiovascular events and bleeding outcomes over time
Trial Details
NCT Number NCT07398001
Lead Sponsor Ulsan University Hospital
Conditions Percutaneous Coronary Intervention, Antiplatelet Therapy, Drug-coated Balloon
Enrollment 1,042 participants
Start Date 2026-02-12
Primary Completion 2028-02-11 (estimated)
Study Completion 2030-07-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-09