Clinical Trial

Treatment of Histamine Intolerance Using Probiotic Intervention

Completed
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to learn if a probiotic product can lower symptoms in adults with histamine intolerance. Histamine intolerance can cause stomach and bowel problems as well as symptoms such as flushing, itching, headaches, and dizziness. The study will also learn how safe and well tolerated the probiotic is. The main questions this study aims to answer are: Does the probiotic lower digestive symptoms linked to histamine intolerance? Does it lower other common symptoms, such as flushing, itching, headaches, or dizziness? Researchers will compare the probiotic to a placebo. A placebo is a look-alike powder that contains no active bacteria. This will help determine whether the probiotic works better than no treatment. Participants will: Take either the probiotic or the placebo once a day for four weeks Visit the study center for screening and two study visits Answer symptom questionnaires Provide blood samples and urine samples The study is for adults with symptoms of histamine intolerance. Participation is voluntary, and participants can stop taking part at any time.
Trial Details
NCT Number NCT07397962
Lead Sponsor University of Hohenheim
Collaborators: Lactopia GmbH, An der Römerbrücke 16, 66121 Saarbrücken, Germany
Conditions Histamin Intolerance
Enrollment 54 participants
Start Date 2024-05-02
Primary Completion 2025-07-25 (estimated)
Study Completion 2025-07-25 (estimated)
Updated on ClinicalTrials.gov 2026-02-09