Clinical Trial

The Application of Intralesional 5-fluorouracil for the Management of Hypertrophic Facial Scars in the Periocular Region Resulting From Trauma and Surgical Procedures in Individuals Aged Over 18 Years

Study acronym: AI5FMHFSPRFSOE
Completed Phase 4
View on ClinicalTrials.gov →
Summary
To determine the effectiveness of intralesional 5-fluorouracil in objectively reversing hypertrophic scars in the periocular region resulting from trauma or cosmetic surgery.
Protocol Amendment History 4 changes
critical Trial completed 2026-06-26
notable Enrollment reduced: 30 -> 7 participants 2026-06-26
notable Primary completion moved earlier: 2026-05-31 -> 2025-11-28 2026-06-26
minor Completion moved earlier: 2026-08-31 -> 2025-11-28 2026-06-26
Trial Details
NCT Number NCT07397520
Lead Sponsor Instituto de Oftalmología Fundación Conde de Valenciana
Conditions Facial Scarring
Enrollment 7 participants
Start Date 2025-08-01
Primary Completion 2025-11-28 (estimated)
Study Completion 2025-11-28 (estimated)
Updated on ClinicalTrials.gov 2026-06-25