Clinical Trial

A Pilot Study to Test the Efficacy of a Commercial Toothpaste (Cosmetic Product)

Recruiting
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Record status
This record was last updated February 9, 2026 (before its estimated July 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
This clinical multi-center, controlled, study will be carried out in volunteers with every 3- to 6-months professional tooth cleaning during their non-treatment period between 2 re-calls of a supportive periodontitis therapy regime. The efficacy of domestic oral hygiene by using a commercial dentifrice will be determined. Besides regularly used ingredients such as NaF and cleaning bodies the dentifrice contains a novel compound, which may be beneficial for the protection of an eubiotic oral microbiome. During the 3-month study period, participants will brush with their allocated study product twice daily.
Trial Details
NCT Number NCT07397312
Lead Sponsor Periotrap Pharmaceuticals GmbH
Conditions Periodontitis
Enrollment 28 participants
Start Date 2025-07-28
Primary Completion 2026-07-31 (estimated)
Study Completion 2026-07-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-09