Clinical Trial

Effectiveness of Surgical and Diagnostic Methods in Cerebral Vascular Occlusive Disease

Enrolling by Invitation
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Summary
This study attempts to improve surgical treatment outcomes among people with chronic carotid artery occlusive disease by conducting a comprehensive review of neuroradiological, clinical, and cognitive data. The evaluation involves an extensive angiographic analysis, including pre- and postoperative measurements of superficial temporal artery branch diameters, assessment of the Circle of Willis and collateral pathways, alongside cerebral perfusion metrics, cognitive status, and clinical outcomes. Major focus is directed towards evaluating the degree of intracranial revascularization following to extracranial-intracranial bypass by postoperative angiographic evaluations. This integrative strategy aims to refine surgical reasons, better predictions of functional and cognitive outcomes, minimize postoperative risks, and eventually improve the overall efficacy of treatment in this patient population.
Trial Details
NCT Number NCT07396025
Lead Sponsor National Centre for Neurosurgery, Republic of Kazakhstan
Conditions Carotid Artery Occlusion
Enrollment 60 participants
Start Date 2025-07-09
Primary Completion 2027-12 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-09