Clinical Trial

Comparing PIEB and CEI for Labor Pain Relief

Study acronym: COPILOT
Recruiting
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Summary
The purpose of this randomized controlled trial is to compare the efficacy and safety of two epidural analgesia maintenance methods for labor pain relief: Programmed Intermittent Epidural Bolus (PIEB) and Continuous Epidural Infusion (CEI), both combined with Patient-Controlled Epidural Analgesia (PCEA). The study aims to evaluate which technique provides superior analgesia while minimizing anesthetic consumption and preserving maternal motor function. A total of 60 parturients at Family Hospital, Da Nang, will be randomly assigned to either the PIEB or CEI group. Outcomes including pain intensity (VAS scores), total drug consumption, maternal satisfaction, and neonatal Apgar scores will be assessed.
Trial Details
NCT Number NCT07395934
Lead Sponsor Da Nang Family General Hospital
Conditions Labor Pain, Analgesia, Epidural, Analgesia, Obstetrical, Labor, Obstetric
Enrollment 60 participants
Start Date 2025-07-30
Primary Completion 2026-08-30 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-09