Clinical Trial

High Frequency Stimulation to Improve Cognition, Mobility, and Affect in Individuals With and Without Subjective Cognitive Decline

Recruiting
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Summary
The goal is to determine whether three months of at least three times / week of sensory flicker stimulation improves cognition, mobility, and affect in healthy older adults and older adults with and without Subjective Cognitive Decline (SCD). Investigators will also determine whether the intervention slows cortical thinning and declines in brain functional network segregation and changes in blood biomarkers of Alzheimer's Disease (AD).
Protocol Amendment History 5 changes
critical Recruitment opened 2026-08-04
critical Primary endpoint(s) modified 2026-08-04
minor Trial arms changed: 4 -> 2 2026-07-28
critical Primary endpoint(s) modified 2026-06-27
minor Trial arms changed: 2 -> 4 2026-05-15
Trial Details
NCT Number NCT07395609
Lead Sponsor University of Florida
Conditions Subjective Cognitive Decline (SCD), Healthy Subjects
Enrollment 60 participants
Start Date 2026-08-03
Primary Completion 2028-10-31 (estimated)
Study Completion 2028-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-03