Clinical Trial

Postoperative Results and Outcomes in Surgical Pelvic Exenteration

Study acronym: PROS-PE
Enrolling by Invitation
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Summary
The purpose of this study is to evaluate the feasibility of a standardized surgical and care process for patients with locally advanced or recurrent rectal cancer that has spread to nearby pelvic organs. When cancer invades adjacent structures (such as the sacrum, bladder, or prostate), a complex procedure called pelvic exenteration (PE) is often required to remove the tumor entirely. This research does not involve testing new or experimental surgical techniques. All procedures performed in this study are part of standard clinical practice. Instead, the focus of this project is to: Standardize Procedures: Create consistent, high-quality steps for the surgical team to follow. Improve Teamwork: Enhance coordination between different medical specialists (such as colorectal surgeons, urologists, and oncologists) to provide better care. Track Outcomes: Use a patient registry to monitor clinical data and quality of life after surgery through patient-reported surveys. A total of 24 adult patients will be enrolled over a three-year period. By refining these workflows and monitoring patient recovery, the study aims to ensure that these complex surgeries are performed as safely and effectively as possible.
Trial Details
NCT Number NCT07395505
Lead Sponsor Chang Gung Memorial Hospital
Conditions Rectal Cancer Recurrent, Pelvic Exenteration, Advanced Rectal Cancer
Enrollment 24 participants
Start Date 2025-11-01
Primary Completion 2028-10-31 (estimated)
Study Completion 2029-02-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-09