Clinical Trial

Using Different Biomaterials to Preserve Bone After Tooth Extraction

Active, Not Recruiting
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Record status
This record was last updated March 27, 2026 (before its estimated April 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This clinical study aims to evaluate the effectiveness of different biomaterials in alveolar socket preservation following tooth extraction. Participants will be allocated into three groups: (1) dentin graft, (2) dentin graft combined with hyaluronic acid, (3) allograft and (4) natural healing without any grafting material (control group). At 4 months post-extraction, dental implants will be placed, and bone biopsies will be obtained during the procedure. These biopsy samples will be subjected to histological analysis to assess new bone formation and graft integration. The study will contribute to the understanding of biomaterial performance in socket preservation prior to implant placement.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-02-05.
Trial Details
NCT Number NCT07394738
Lead Sponsor Inonu University
Conditions Alveolar Ridge Preservation, Bone Regeneration, Tooth Extraction, Dental Implants
Enrollment 40 participants
Start Date 2025-04-09
Primary Completion 2026-04-30 (estimated)
Study Completion 2026-06 (estimated)
Updated on ClinicalTrials.gov 2026-03-27