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Using Different Biomaterials to Preserve Bone After Tooth Extraction

StatusCompleted
PhaseNot applicable
Started
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Record History

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  1. Primary endpoint(s) modified Show 6 more changesShow less
    • Start date: Apr 9, 2025 to Feb 9, 2026
    • Trial completed
    • Primary completion date changed from estimate of Apr 30, 2026 to Jun 30, 2026
    • Secondary endpoints revised (7)
    • Study description expanded, about 21 words
    • Eligibility criteria expanded, about 2 words
  2. Primary completion date: Mar 2026 to Apr 30, 2026
    • Study description expanded, about 8 words
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Inonu University
150 trials monitored
See 3 trials at risk
This four-arm randomized controlled clinical trial evaluated the clinical, radiographic, and histological outcomes of different approaches to alveolar ridge preservation following tooth extraction. Forty systemically healthy adults requiring extraction of a maxillary non-molar tooth and subsequent implant placement were randomly allocated to autogenous dentin graft, autogenous dentin graft combined with hyaluronic acid, allograft, or spontaneous healing groups (n = 10/group). Clinical and cone-beam computed tomography assessments were performed at baseline and 4 months. During implant placement at 4 months, bone core biopsies were obtained from all study sites and subjected to histological, histomorphometric, and immunohistochemical analyses.
Trial Details
NCT Number NCT07394738
Lead Sponsor Inonu University
Conditions
(from sponsor)		 Alveolar Ridge Preservation, Bone Regeneration, Tooth Extraction, Dental Implants
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov