Clinical Trial

Rectus Sheath Block as an Adjunct to General Anesthesia for Midline Laparotomy Pain

Study acronym: RSB-MIDLINE
Completed
View on ClinicalTrials.gov →
Summary
This study evaluates whether adding an ultrasound-guided rectus sheath block (RSB) to general anesthesia can improve pain control after midline laparotomy. Adult patients undergoing midline incision laparotomy will be randomly assigned to receive either general anesthesia alone or general anesthesia plus bilateral RSB with local anesthetic (bupivacaine 0.25%). After surgery, pain will be assessed using the Numeric Rating Scale (NRS) at 15 minutes, 1 hour, 3 hours, 6 hours, 12 hours, and 24 hours. The study will also compare the time to first opioid request, total opioid use during the first 24 hours after surgery, and changes in inflammation measured by the neutrophil-to-lymphocyte ratio (NLR). The goal is to determine whether RSB can reduce postoperative pain and opioid requirements and help limit postoperative inflammatory response.
Trial Details
NCT Number NCT07393763
Lead Sponsor Udayana University
Collaborators: RSUP Prof. Dr. I.G.N.G. Ngoerahal
Conditions Postoperative Pain, Abdominal Surgery by Laparotomy
Enrollment 46 participants
Start Date 2022-02-01
Primary Completion 2022-04-30 (estimated)
Study Completion 2022-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-06