Predictive Value of aEEG and Cerebral Oxygenation on Neurological Outcomes in Newborns With Mild Hypoxic-Ischemic Encephalopathy

Newborns with mild hypoxic-ischemic encephalopathy usually do not receive cooling treatment. However, some of these newborns may develop neurological problems later in life. This observational study aims to evaluate whether early brain monitoring and measurements of brain oxygen levels are associated with neurological outcomes in newborns with mild hypoxic-ischemic encephalopathy. Newborns will be monitored during the first 72 hours after birth as part of routine clinical care. Neurological assessments will be performed during early infancy and later follow-up. The findings of this study may help improve early risk assessment and support closer monitoring of newborns who may be at increased risk for unfavorable neurological outcomes.

NCT Number	NCT07393620
Lead Sponsor	Uludag University
Conditions	Hypoxic-Ischemic Encephalopathy Mild
Enrollment	30 participants
Start Date	2026-02-10
Primary Completion	2027-02-10 (estimated)
Study Completion	2029-02-10 (estimated)
Updated on ClinicalTrials.gov	2026-05-01