Clinical Trial

Effect of Probiotics on Constipation and Weight in CP

Study acronym: cerebral palsy
Completed
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Summary
The goal of this clinical trial is to learn whether using Lactobacillus reuteri or a prebiotic-containing Lactobacillus rhamnosus supplement helps to improve constipation and weight gain in children with cerebral palsy (CP). It will also examine the safety and tolerability of these probiotic products. The main questions it aims to answer are: Do these probiotic supplements improve bowel movement frequency and stool consistency? Do they support better weight gain and nutritional status in children with CP? Are there any side effects or tolerability issues during treatment? Researchers will compare Lactobacillus reuteri with prebiotic-enriched Lactobacillus rhamnosus in a randomized, double-blind, controlled design. Participants will: Take one of the probiotic products daily for 28 days Visit the clinic at the beginning and end of the study for measurements and stool testing Have their caregivers keep a stool diary using the Bristol stool scale
Trial Details
NCT Number NCT07393256
Lead Sponsor Ordu University
Conditions Cerebral Palsy (CP), Constipation, Probiotic
Enrollment 30 participants
Start Date 2022-11-01
Primary Completion 2025-03-29 (estimated)
Study Completion 2025-04-29 (estimated)
Updated on ClinicalTrials.gov 2026-02-06