Clinical Trial

Feasibility Study of Diaphragm Synchronized Pacing (DSP) Via the Left Inferior Phrenic Vein (LIPV) Approach

Recruiting
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Record status
This record was last updated February 6, 2026 (before its estimated February 28, 2026 completion). Its status may not reflect the trial's current state.
Summary
Cardiac resynchronization therapy(CRT) benefits a portion of patients, while more patients are not yet indicated to a therapy that mechanically helps the heart systole and/or diastole. Synchronized diaphragmatic pacing may be feasible to induce diaphragm local contraction and recoil that enhance pump function of the heart, thus improve cardiac function and QoL. This acute, interventional study is conducted in a single site, Renji Hospital, to evaluate the feasibility of diaphragm pacing and assess the beneficial effect of pacing-regulated diaphragm movement to the heart, with 10 cases of sample size and one-week follow-up after discharge.
Trial Details
NCT Number NCT07392749
Lead Sponsor RenJi Hospital
Conditions Heart Failure
Enrollment 10 participants
Start Date 2025-11-28
Primary Completion 2026-02-28 (estimated)
Study Completion 2026-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-06