Clinical Trial

Prospective Validation of an AI Model for Predicting Liver Metastasis in Colorectal Cancer

Recruiting
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Summary
This is a prospective, multicenter, observational study designed to validate the predictive accuracy of a pre-developed multimodal deep learning model. The model integrates preoperative contrast-enhanced CT scans, digitized postoperative pathology images, and standard clinical data to estimate the risk of liver metastasis within two years after curative surgery in patients with stage I-III colorectal cancer. The primary objective is to evaluate the model's performance in an independent, prospectively enrolled patient cohort. Participants will receive standard-of-care treatment according to clinical guidelines. The study involves no experimental interventions; it solely involves the collection and analysis of routinely generated clinical data. The goal is to assess the model's potential for clinical translation by providing a reliable tool for stratifying patients' risk of liver metastasis, which could inform personalized surveillance strategies.
Trial Details
NCT Number NCT07392567
Lead Sponsor Tongji Hospital
Conditions Colorectal Cancer Liver Metastasis
Enrollment 160 participants
Start Date 2026-01-30
Primary Completion 2028-01-30 (estimated)
Study Completion 2029-01-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-06