Clinical Trial

Efficacy of Tranexamic Acid Reducing Blood Loss During Maxillofacial Trauma Surgery

Completed Phase 2
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Summary
Tranexamic acid (TXA) is an inexpensive, easily used and relatively safe drug. It inhibits plasminogen activation and plasmin thus retards clot disintegration.Therapeutic application of tranexamic acid in trauma for preventing blood loss has been documented since long. Since blood loss causes several serious complications, it is compensated emergently by transfusion of blood or its products. However, transfusion of blood and products always carries a risk of inadvertent transmission of infection, antigen-antibody reactions and additional cost all of which can be prevented if blood loss is reduced. Morbidity associated with the delay in compensating the blood loss could also be prevented by pharmaceutically preventing hemorrhage.
Trial Details
NCT Number NCT07392034
Lead Sponsor Nishtar Medical University
Conditions Hemoglobin Level Measurement, Blood Loss During Surgery, Duration of Surgery
Enrollment 60 participants
Start Date 2025-01-01
Primary Completion 2025-06-30 (estimated)
Study Completion 2025-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-06