Clinical Trial

Peripheral Perfusion and Outcomes in ICU Patients With Sepsis

Study acronym: PERFUSE-ICU
Not Yet Recruiting
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Record status
This record was last updated February 9, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
People with sepsis who are treated in the intensive care unit (ICU) often have impaired blood flow to the skin and other tissues. These alterations in tissue perfusion may be associated with disease severity and clinical outcomes. The aim of this study is to see whether simple signs of blood flow to the skin, such as capillary refill time and blood test measurements, are linked to outcomes in people with sepsis treated in the ICU. Adults with sepsis who are admitted to the ICU will be invited to take part. Researchers will collect routine clinical data and blood test results during the first day of ICU treatment. No extra procedures or treatments will be performed as part of the study. The results of this study may improve understanding of early signs of impaired circulation in sepsis and their relation with recovery and survival.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-01-29.
Trial Details
NCT Number NCT07391098
Lead Sponsor Alexandra Elena Lazăr
Conditions SEPSIS, Septic Patients
Enrollment 80 participants
Start Date 2026-02-02
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-09