Clinical Trial

GLS in Difficult CPB Weaning

Recruiting
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Record status
This record was last updated February 5, 2026 (before its estimated July 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to learn whether global longitudinal strain (GLS), measured by echocardiography, can predict difficulty separating from cardiopulmonary bypass (CPB) in adults undergoing elective cardiac surgery. The main questions it aims to answer are: * Can preoperative GLS measurement predict difficult separation from CPB? * Are GLS values associated with outcomes such as intensive care unit (ICU) stay, hospital stay, cardiac biomarkers, or 30-day mortality? Participants will: * Undergo standard cardiac surgery requiring CPB * Have echocardiographic assessments (TTE before and after surgery) * Have their recovery and outcomes monitored, including ICU and hospital stay, postoperative labs, and survival within 30 days
Trial Details
NCT Number NCT07390903
Lead Sponsor Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Collaborators: University of Rome Tor Vergata, San Raffaele University Hospital, Italy
Conditions Cardiopulmonary Bypass, Coronary Artery Bypass, Heart Valve Diseases, Echocardiography, Intraoperative Complications, Postoperative Complications (Cardiopulmonary)
Enrollment 213 participants
Start Date 2026-02-05
Primary Completion 2026-07-30 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-05