Bowel Continence Across the Lifespan in People With Spina Bifida

The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida. An enema program involves putting liquid into the large intestine (colon) to help someone poop. The main questions it aims to answer are: 1. How well do different enema programs prevent bowel accidents? 2. How do these enema programs affect independence, bowel symptoms, and quality of life? Researchers will compare two types of enema programs to see which works better and is easier for participants to manage. Participants starting a new enema program will answer online survey questions at 3 different timepoints over the course of 1 year.

NCT Number	NCT07390318
Lead Sponsor	David Chu Collaborators: Patient-Centered Outcomes Research Institute
Conditions	Spina Bifida, Neurogenic Bowel, Bowel Incontinence
Enrollment	943 participants
Start Date	2026-04-01
Primary Completion	2030-05-01 (estimated)
Study Completion	2030-05-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-21