Clinical Trial

Personalized Music and Dreaming During Propofol Sedation

Completed
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Summary
Many patients report dreams during intravenous (IV) propofol sedation, but it is uncertain whether listening to music changes how often dreams occur or how pleasant they feel. This single-center randomized study compared three auditory conditions during propofol sedation for elective surgery under spinal anesthesia or peripheral nerve block: (1) patient-selected preferred music, (2) matched non-preferred music, and (3) silence (headphones only). Music or silence was delivered through identical closed-back headphones starting 1-2 minutes before sedation and continuing until the end of sedation. The main outcomes were (1) whether a dream occurred (yes/no) assessed by a neutral modified Brice interview in the post-anesthesia care unit (PACU), and (2) dream pleasantness rated on a 0-10 scale among participants who reported a dream. Additional outcomes included coded dream content features, patient satisfaction, sedative dose, hemodynamic variability, early recovery measures, postoperative symptoms, and adverse events.
Trial Details
NCT Number NCT07389954
Lead Sponsor Wonkwang University Hospital
Conditions Conscious Sedation, Propofol, Dreams
Enrollment 300 participants
Start Date 2025-12-19
Primary Completion 2026-01-16 (estimated)
Study Completion 2026-01-16 (estimated)
Updated on ClinicalTrials.gov 2026-02-05