Clinical Trial

INVESTIGATION OF THE EFFECT OF DIFFERENT ACTIVATION TECHNIQUES ON TLR9, IL6, IL10, TNF-ALFA LEVELS IN HEALTHY AND TYPE 2 DIABETIC PATIENTS WITH APICAL PERIODONTITIS REQUIRING RETREATMENT

Study acronym: TLR9 in T2DM
Enrolling by Invitation
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Record status
This record was last updated February 10, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The subject of this thesis study is the effects of SWEEPS laser and ultrasonic activation methods on the immune response in the treatment of apical periodontitis in healthy individuals and patients with Type 2 diabetes requiring retreatment, based on a comparative investigation of Toll-like Receptor 9 (TLR-9), Interleukin-6 (IL-6) and Tumour Necrosis Factor alpha (TNF-α), and Interleukin-10 (IL-10) levels.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-01-29.
Trial Details
NCT Number NCT07389772
Lead Sponsor bengisu yüksel
Conditions Type 2 Diabetes
Enrollment 90 participants
Start Date 2026-01-28
Primary Completion 2026-06-30 (estimated)
Study Completion 2027-05-15 (estimated)
Updated on ClinicalTrials.gov 2026-02-10