Clinical Trial

Individualized Open Lung Ventilation and Postoperative Pulmonary Complications in Thoracic Surgery

Not Yet Recruiting
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Record status
This record was last updated February 4, 2026 (before its estimated April 10, 2026 completion). Its status may not reflect the trial's current state.
Summary
This prospective, single-center, randomized controlled trial aims to evaluate the efficacy of an intraoperative "Individualized Open Lung Ventilation" strategy compared to a standard lung-protective ventilation strategy in patients undergoing thoracic surgery. One-lung ventilation (OLV) is essential for thoracic surgery but can cause lung injury. While standard care often uses fixed ventilation parameters, this study investigates whether personalizing Positive End-Expiratory Pressure (PEEP) to achieve the lowest driving pressure can reduce the incidence of postoperative pulmonary complications (PPCs) within 7 days after surgery.
Trial Details
NCT Number NCT07387822
Lead Sponsor Aerospace Center Hospital
Conditions Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV), Thoracic Surgery, Video Assisted
Enrollment 352 participants
Start Date 2026-02-10
Primary Completion 2026-04-10 (estimated)
Study Completion 2026-05-10 (estimated)
Updated on ClinicalTrials.gov 2026-02-04