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Individualized Open Lung Ventilation and Postoperative Pulmonary Complications in Thoracic Surgery

StatusNot Yet Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 4, 2026 (before its estimated April 10, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
This prospective, single-center, randomized controlled trial aims to evaluate the efficacy of an intraoperative "Individualized Open Lung Ventilation" strategy compared to a standard lung-protective ventilation strategy in patients undergoing thoracic surgery. One-lung ventilation (OLV) is essential for thoracic surgery but can cause lung injury. While standard care often uses fixed ventilation parameters, this study investigates whether personalizing Positive End-Expiratory Pressure (PEEP) to achieve the lowest driving pressure can reduce the incidence of postoperative pulmonary complications (PPCs) within 7 days after surgery.
Trial Details
NCT Number NCT07387822
Lead Sponsor Aerospace Center Hospital
Conditions
(from sponsor)		 Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV), Thoracic Surgery, Video Assisted
Enrollment 352 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov