Imaging Acetadote Metabolism in Glioblastoma

This goal of this clinical trial is to evaluate how Acetadote affects metabolism in patients with glioblastoma. Drugs like Acetadote, which affect the level of damage in a cell (oxidative stress), may impact brain tumor metabolism and slow the growth of brain tumors. The investigators are evaluating how Acetadote affects glioblastoma metabolism by using MRI-based methods and by determining the changes in metabolism in brain tumor tissue resected from patients with a new diagnosis of glioblastoma.

NCT Number	NCT07387666
Lead Sponsor	University of Texas Southwestern Medical Center Collaborators: Cumberland Pharmaceuticals
Conditions	Glioblastoma, GBM
Enrollment	10 participants
Start Date	2026-06-18
Primary Completion	2027-07-01 (estimated)
Study Completion	2028-07-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-23