The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma

The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma. The study will include patients for whom surgical treatment of bowel endometriosis is clinically indicated. This research would represent a significant advancement in evaluating the necessity of surgical intervention in asymptomatic patients or those with mild symptoms. Furthermore, it would provide a broader insight into the systemic impact of endometriosis on other organ systems, ultimately improving risk assessment and preventive measures.

NCT Number	NCT07386431
Lead Sponsor	University Medical Centre Ljubljana
Conditions	Endometriosis, Deep Endometriosis, Bowel Endometriosis, Colorectal Carcinoma, Colon Resection, Endometriosis Pelvic, Endometriosis Rectum, Carcinogenesis +2 more
Enrollment	30 participants
Start Date	2026-02
Primary Completion	2028-10 (estimated)
Study Completion	2029-05 (estimated)
Updated on ClinicalTrials.gov	2026-02-06