Collagenic vs Collagen-enriched Graft in Sinus Elevation: RCT

The goal of this clinical trial is to histologically understand if collagenic or collagen enriched graft in sinus lift of healthy volunteers needing for implants in the posterior maxillae may work. The main question it aims to answer are: which material works better histologically and radiologically? Researchers will compare a collagenic graft to collagen enriched graft to see if the osteointegration of the material is the same. Participants will undergo a sinus lift with one of the two materials and after six month will undergo a bone sample collection to allow the implant insertion. twelve moths thereafter, a radiograph will be taken to measure the extension of the bone regeneration and implant behavior

NCT Number	NCT07386184
Lead Sponsor	Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Conditions	Sinus Lift Augmentation
Enrollment	24 participants
Start Date	2026-03-19
Primary Completion	2027-06-01 (estimated)
Study Completion	2027-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-10