Clinical Trial

Electroporation Treatment for Early AF Management in Heart Failure With Preserved Ejection Fraction (HFpEF) Pilot Study

Study acronym: E-TEAM
Recruiting
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Record status
This record was last updated February 4, 2026 (before its estimated April 12, 2026 completion). Its status may not reflect the trial's current state.
Summary
The proposed pilot study is a prospective, randomized, single-center feasibility study, enrolling 200 patients with symptomatic paroxysmal AF. Per protocol, 100 patients will undergo a FARAPULSE electroporation PVI and 100 patients will receive standard AF medical treatment. Prior enrollment, all patients will be informed on the risk and benefits of the PVI procedure as well as the medical treatment. In addition, particular information on the rationale of the study, including a detailed risk/benefit analysis, will be provided to all patients.
Trial Details
NCT Number NCT07385417
Lead Sponsor Cardioangiologisches Centrum Bethanien
Conditions Atrial Fibrillation (AF)
Enrollment 200 participants
Start Date 2023-04-12
Primary Completion 2026-04-12 (estimated)
Study Completion 2026-04-12 (estimated)
Updated on ClinicalTrials.gov 2026-02-04