Clinical Trial

Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients

Recruiting
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Summary
The aim of this study is to evaluate the relationship between the severity of Pemphigus Vulgaris (a chronic autoimmune skin disease) and periodontal (gum) health. Researchers will assess disease activity using the Oral Disease Severity Score (ODSS) for mouth lesions and measure serum Desmoglein 1 and 3 levels through blood tests. These findings will be compared with clinical gum measurements, such as pocket depth and attachment levels. The study intends to determine how the clinical and biochemical severity of Pemphigus Vulgaris impacts periodontal tissues and overall oral health.
Trial Details
NCT Number NCT07384221
Lead Sponsor Saglik Bilimleri Universitesi
Conditions Pemphigus Vulgaris (PV), Periodontal Diseases
Enrollment 20 participants
Start Date 2025-11-01
Primary Completion 2026-01-30 (estimated)
Study Completion 2026-02-21 (estimated)
Updated on ClinicalTrials.gov 2026-02-03