Remote Ischemic Preconditioning for Aute Type A Aortic Dissection Surgery

The goal of this clinical trial is to learn if a technique called remote ischemic preconditioning (RIPC) helps protect organs during emergency surgery for acute type A aortic dissection (ATAAD). The main questions it aims to answer are: Does RIPC reduce the risk of major complications after surgery, such as heart, brain, or kidney problems? Is RIPC safe to use during emergency ATAAD surgery? Researchers will compare the RIPC group to a control group (who will receive a placebo) to see if RIPC can reduce complications after surgery. Participants will: Receive either RIPC or a sham intervention during their surgery. Be monitored for up to 30 days after surgery for complications. Have follow-up visits at 3 months, 1 year, and then yearly for up to 5 years to track their recovery.

NCT Number	NCT07383909
Lead Sponsor	Fujian Medical University Collaborators: The First Affiliated Hospital of Dalian Medical University, Xiamen Cardiovascular Hospital, Xiamen University
Conditions	Aortic Dissection Type A
Enrollment	1,296 participants
Start Date	2026-01-05
Primary Completion	2029-01-31 (estimated)
Study Completion	2032-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-03