Clinical Trial

Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Ulcerative Colitis and Crohn Disease

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Summary
The goal of the study is to evaluate the safety and efficacy of multimodal (cytokine and lipopolysaccharide) hemoperfusion using the Efferon® LPS device in patients with ulcerative colitis and Crohn disease. Participants will be assigned to two groups for comparison: a control group receiving baseline therapy and a treatment group receiving baseline therapy in combination with Efferon® LPS hemoadsorption.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-01-26.
Trial Details
NCT Number NCT07383597
Lead Sponsor Efferon JSC
Conditions Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
Enrollment 40 participants
Start Date 2026-03-01
Primary Completion 2027-09-01 (estimated)
Study Completion 2028-03-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-11