Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure

The goal of this clinical trial is to learn if the combination between transcutaneous electrical nerve stimulation (TENS) and isometric exercise (IE) can improve blood pressure in men and women between 50 to 60 years old suffered from resistant hypertension which is a type of hypertension where blood pressure remains above your target goal despite the use of three or more different classes of antihypertensive medications at their maximum tolerated doses. The main question to answer is: Is there a significant effect on the combined use of TENS and IE on peripheral hemodynamic parameters in patients with resistant hypertension? Total sample will be 50 patients from both sexes I will compare between two groups: Experimental group (15 men, 10 women) will take: medication plus IE and TENS Control group (15 men, 10 women) will take: medication plus Conventional Physical Therapy Program

NCT Number	NCT07383220
Lead Sponsor	Mohamed Mohamed Ali Morgan
Conditions	Resistant Hypertension, Hemodynamic Instability, Essential (Primary) Hypertension, Abdominal Obesity, Metabolic Syndrome, Hypertension (HTN), Vascular Resistance, High Blood Pressure
Enrollment	50 participants
Start Date	2026-01-15
Primary Completion	2026-05-30 (estimated)
Study Completion	2026-06-10 (estimated)
Updated on ClinicalTrials.gov	2026-02-03