Zesty Exercise System for Therapeutic Engagement

This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely. Participants will complete robot-guided exercise three times per week for three weeks. The study will assess feasibility, retention, safety, acceptability, and tolerability of remotely monitored ZEST-E and will measure changes in functional performance using the Standing Forward Reach test and the 30-Second Chair Stand test. These outcomes reflect range of motion and lower-body strength targeted by the exercise program.

NCT Number	NCT07382674
Lead Sponsor	Emory University Collaborators: Georgia Clinical & Translational Science Alliance
Conditions	Parkinson Disease
Enrollment	46 participants
Start Date	2026-03-16
Primary Completion	2028-02 (estimated)
Study Completion	2028-02 (estimated)
Updated on ClinicalTrials.gov	2026-05-26