Clinical Trial

Effect of PAE Hydrogel Loaded With tRF-ASO-Exo on Patients With Diabetic Ocular Surface Diseases

Not Yet Recruiting Phase 2
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Summary
The purpose of this study is to determine whether poly（β-amino ester）(PAE)hydrogel loaded with tRNA-derived fragments-antisense oligonucleotides-exosomes(tRF-ASO-Exo) could alleviate symptoms in patients with diabetic ocular surface diseases(DOSD).
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-01-27.
Trial Details
NCT Number NCT07382453
Lead Sponsor Affiliated Hospital of Nantong University
Conditions Diabetic Keratopathy
Enrollment 30 participants
Start Date 2026-02-15
Primary Completion 2028-12-30 (estimated)
Study Completion 2029-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-04