Correlation of Oxygenation and Saturation Indices in One-Lung Ventilation

One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics. Traditional oxygenation indices require arterial blood gas analysis and do not fully reflect the mechanical stress applied to the lungs. This prospective observational study aims to evaluate the correlation between oxygenation indices and oxygen saturation indices during one-lung ventilation in adult patients undergoing elective thoracic surgery. Modified indices incorporating driving pressure and mechanical power will also be assessed. No intervention beyond standard clinical care will be applied. The findings of this study may help clarify the clinical utility of non-invasive oxygenation indices for intraoperative monitoring during one-lung ventilation.

NCT Number	NCT07381517
Lead Sponsor	Ankara Ataturk Sanatorium Training and Research Hospital
Conditions	One-lung Ventilation (OLV)
Enrollment	51 participants
Start Date	2026-02-09
Primary Completion	2026-06-09 (estimated)
Study Completion	2026-08-09 (estimated)
Updated on ClinicalTrials.gov	2026-02-02