Clinical Trial

ARNI Combined With SGLT2 Inhibitors on Functional Mitral Regurgitation Remodeling

Name: ARNI Combined With SGLT2 Inhibitors on Functional Mitral Regurgitation Remodeling — clinical trial record (NCT07379788)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Completed

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Summary

This study aimed to compare the effects of ARNI monotherapy versus combined ARNI and SGLT2 inhibitor therapy on Mitral Remodeling Index (MRIx) and Functional mitral regurgitation (FMR) remodeling in patients with heart failure with reduced ejection fraction (HFrEF).

Protocol Amendment History 1 change

critical Trial completed 2026-04-22

Trial Details

NCT Number	NCT07379788
Lead Sponsor	Rehab Werida Collaborators: Tanta University
Conditions	Heart Failure
Enrollment	180 participants
Start Date	2025-01-01
Primary Completion	2026-02-28 (estimated)
Study Completion	2026-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-02