Towards Causal Mapping of Episodic Memory iEEG Networks Via Multi-method Brain Stimulation

Human intracranial electroencephalography (EEG) can provide brain-activity correlates of memory with high spatial and temporal resolution. This project will test functional relevance of these neural signals for memory behavioral performance using novel noninvasive and invasive stimulation methods. Findings will advance understanding of brain mechanisms for memory, as is needed to accelerate progress in the treatment of memory disorders.

NCT Number	NCT07378332
Lead Sponsor	University of Chicago Collaborators: Northwestern University, Washington University School of Medicine
Conditions	Memory Performance, Hippocampal Activity
Enrollment	44 participants
Start Date	2025-09-15
Primary Completion	2028-04-30 (estimated)
Study Completion	2028-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-01-30