Clinical Trial

Carbonic Anhydrase II Responses to Basketball-Specific High-Intensity Interval Training

Study acronym: CAII-BASKET
Completed
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Summary
This study aims to examine whether erythrocyte carbonic anhydrase II can be used as a biological marker of metabolic adaptation to basketball-specific high-intensity interval training. Carbonic anhydrase II is an enzyme involved in acid-base balance and carbon dioxide transport, and it may reflect physiological adaptations to intense exercise. Healthy basketball players participated in a structured high-intensity interval training program designed to reflect the physical demands of basketball. Blood samples and performance-related measurements were collected before and after the training period to evaluate changes in erythrocyte carbonic anhydrase II levels and related metabolic responses. The findings of this study are expected to improve the understanding of exercise-induced metabolic adaptations and to explore the potential use of erythrocyte carbonic anhydrase II as a practical biomarker for monitoring training responses in basketball players.
Trial Details
NCT Number NCT07377851
Lead Sponsor Karamanoğlu Mehmetbey University
Conditions Metabolic Adaptation to High-Intensity Interval Training
Enrollment 24 participants
Start Date 2025-11-01
Primary Completion 2026-01-10 (estimated)
Study Completion 2026-01-15 (estimated)
Updated on ClinicalTrials.gov 2026-01-30