Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple Myeloma

A randomized, parallel, double-blind, controlled, clinical trial. Two groups of participants will be included, both receiving a therapeutic exercise intervention and an educational session on the importance of proper breathing over a 6-week period. One of the groups will additionally perform a home-based controlled breathing exercise protocol. Pre- and post-intervention assessments (6 weeks) will be conducted, along with a follow-up evaluation 4 weeks after completion of the intervention. The goal is to determine the effectiveness of adding a controlled breathing exercise program to a therapeutic exercise intervention on cardiorespiratory variables in individuals with multiple myeloma.

NCT Number	NCT07376733
Lead Sponsor	Universidad Complutense de Madrid
Conditions	Multiple Myeloma (MM), Breathing Techniques, Breathing Exercises, Exercise Activity, Diaphragmatic Breathing, Heart Rate Variability (HRV)
Enrollment	26 participants
Start Date	2026-01
Primary Completion	2026-06 (estimated)
Study Completion	2026-09 (estimated)
Updated on ClinicalTrials.gov	2026-01-29