Clinical Trial

Intraoperative Ultrasound for Brain Tumor Surgery Enhanced by AI

Study acronym: BrainUS-AI
Not Yet Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
Intraoperative ultrasound is a versatile, low-cost imaging tool that has been shown to improve safety and efficacy in brain tumor surgery. However, its widespread adoption remains limited due to operator dependency, the complexity of image interpretation, the presence of artifacts, and a restricted field of view. This project aims to prospectively evaluate, in a multicenter and non-randomized setting, a prototype real-time deep learning-based segmentation model for brain tumor delineation in intraoperative ultrasound. The model is designed to facilitate the identification of tumor tissue during surgery, potentially enhancing intraoperative decision-making and surgical precision. By increasing the precision and accessibility of ioUS, this innovation is expected to enable safer and more complete resections, with the potential to improve both survival and quality of life for patients with brain tumors.
Trial Details
NCT Number NCT07376304
Lead Sponsor Hospital del Rio Hortega
Collaborators: University Hospital Bratislava
Conditions Brain Tumor Adult
Enrollment 100 participants
Start Date 2026-03
Primary Completion 2027-12 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-01-29