Clinical Trial

Predictors of Clinical Outcomes of Deep Brain Stimulation in Parkinson's Disease

Recruiting
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Summary
The goal of this observational study is to identify factors in blood that are associated with response to deep brain stimulation (DBS) surgery in patients with Parkinson's disease. The main questions it aims to answer are: 1. What factors in blood (proteins and RNA) are associated with good vs poor response to DBS? 2. Are these factors able to predict response to DBS? 3. How do these factors change before and after DBS? Blood and leftover brain tissue (which spontaneously adhere to the surgical instruments) will be taken and routine clinical data (including scores from routine assessments) will be collected from consenting participants who undergo DBS.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2026-01-22; most recent amendment 2026-02-23.
Status change: Not Yet Recruiting → Recruiting 2026-02-23
Trial Details
NCT Number NCT07376278
Lead Sponsor Hong Kong University of Science and Technology
Collaborators: Queen Elizabeth Hospital, Hong Kong, Hong Kong Center for Neurodegenerative Diseases
Conditions Deep Brain Stimulation, PARKINSON DISEASE (Disorder)
Enrollment 30 participants
Start Date 2026-02-05
Primary Completion 2036-02-01 (estimated)
Study Completion 2038-02-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-24